The 23rd installment in the James Bond franchise surpasses the benchmark after only four days in nationwide release.
Sam Mendes' Skyfall grossed a healthy $11.3 million on Monday -- Veteran's Day -- boosting its domestic cume to $101.9 million after only four days in nationwide release.
From EON Productions, MGM and Sony, the 23rd installment in the James Bond franchise brings back Daniel Craig as 007 for a third time.
Skyfall opened in North America on Thursday in select IMAX and other large-format theaters, grossing $2.2 million. Debuting everywhere on Friday, the movie grossed $88.4 million for the weekend -- easily the top domestic opening for a Bond pic, not accounting for inflation.
Skyfall is doing massive business overseas, where it has earned north of $430 million since rolling out two weeks ago.
The movie is certain to surpass the $576.1 million earned by Quantum of Solace and the $599.2 million grossed by Casino Royale in their entire worldwide runs.
Skyfall has generated stellar numbers for IMAX theaters, which have sold north of $30 million in tickets globally.
This time out, cinema's most famous spy must save both M -- again played by Judi Dench -- and MI6 from former operative-turned-villain Raoul Silva (Javier Bardem). The movie also stars Ralph Fiennes, Naomie Harris, Berenice Lim Marlohe and Albert Finney.